Antiviral and immunomodulatory interferon-beta in high-risk COVID-19 patients: a structured summary of a study protocol for a randomised controlled trial

Antiviral and immunomodulatory interferon-beta in high-risk COVID-19 patients: a structured summary of a study protocol for a randomised controlled trial

Abstract Objectives The primary objective of the study is to demonstrate the efficacy of low-dose IFN-β in reducing the risk of SARS-CoV-2 recently infected elderly patients to progress towards severe COVID-19 versus control group within 28 days. Secondary objectives are: 1) To assess the reduction...

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Bibliographic Details
Main Authors: Eleonora Aricò, Luciano Castiello, Laura Bracci, Francesca Urbani, Flavia Lombardo, Ilaria Bacigalupo, Antonio Ancidoni, Nicola Vanacore, Alessandro Falcione, Chiara Reggiani, Giovanni Marco Dutti, Maria Grazia Maglie, Ombretta Papa, Pier Luigi Bartoletti, Giuseppina Ozzella, Nazario Bevilacqua, Emanuele Nicastri, Filippo Belardelli, Giuseppe Sconocchia
Format: Article
Language:English
Published: BMC 2021-09-01
Series:Trials
Subjects:
COVID-19
Randomised controlled trial
protocol
Interferon-beta
antiviral
immunomodulation
Online Access:https://doi.org/10.1186/s13063-021-05367-6

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