Inhibitory effects of HNF4α on migration/maltransformation of hepatic progenitors: HNF4α-overexpressing hepatic progenitors for liver repopulation

Inhibitory effects of HNF4α on migration/maltransformation of hepatic progenitors: HNF4α-overexpressing hepatic progenitors for liver repopulation

Abstract Background Although they are expandable in vitro, hepatic progenitors are immature cells and share many immunomarkers with hepatocellular carcinoma, raising potential concerns regarding maltransformation after transplantation. This study investigated the effects of hepatic nuclear factor (H...

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Bibliographic Details
Main Authors: Ping Wang, Min Cong, Tianhui Liu, Hufeng Xu, Lin Wang, Guangyong Sun, Aiting Yang, Dong Zhang, Jian Huang, Yameng Sun, Wenshan Zhao, Hong Ma, Jidong Jia, Hong You
Format: Article
Language:English
Published: BMC 2017-08-01
Series:Stem Cell Research & Therapy
Subjects:
Hepatic nuclear factor 4α
Hepatic progenitors
Proliferation
Liver repopulation
Online Access:http://link.springer.com/article/10.1186/s13287-017-0629-8

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