Molecular Pathways Modulated by Mesenchymal Stromal Cells and Their Extracellular Vesicles in Experimental Models of Liver Fibrosis

Molecular Pathways Modulated by Mesenchymal Stromal Cells and Their Extracellular Vesicles in Experimental Models of Liver Fibrosis

End-stage liver fibrosis is common to all chronic liver diseases. Since liver transplantation has several limitations, including lack of donors, immunological rejection, and high medical costs, therapeutic alternatives are needed. The administration of mesenchymal stromal cells (MSCs) has been prove...

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Bibliographic Details
Main Authors: Giulia Chiabotto, Chiara Pasquino, Giovanni Camussi, Stefania Bruno
Format: Article
Language:English
Published: Frontiers Media S.A. 2020-12-01
Series:Frontiers in Cell and Developmental Biology
Subjects:
mesenchymal stem cell
collagen
α-SMA
hepatic stellate cell
fibrosis
inflammation
Online Access:https://www.frontiersin.org/articles/10.3389/fcell.2020.594794/full

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