Aluminum hydroxide associated to Schistosoma mansoni 22.6 kDa protein abrogates partial protection against experimental infection but not alter interleukin-10 production

Aluminum hydroxide associated to Schistosoma mansoni 22.6 kDa protein abrogates partial protection against experimental infection but not alter interleukin-10 production

The need to develop a vaccine against schistosomiasis led several researches and our group to investigate proteins from Schistosoma mansoni as vaccine candidates. Sm22.6 is a protein from S. mansoni that shows high identity with Sj22.6 and Sh22.6 (79 and 91%, respectively). These proteins are associ...

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Bibliographic Details
Main Authors: Lucila GG Pacífico, Cristina T Fonseca, Michele M Barsante, Luciana S Cardoso, Maria Ilma Araújo, Sérgio C Oliveira
Format: Article
Language:English
Published: Instituto Oswaldo Cruz, Ministério da Saúde 2006-10-01
Series:Memórias do Instituto Oswaldo Cruz.
Subjects:
Schistosoma mansoni
Sm22.6
recombinant vaccine
aluminum hydroxide
adjuvant
interleukin-10
Online Access:http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0074-02762006000900060

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