Application and Progress of Combined Mesenchymal Stem Cell Transplantation in the Treatment of Ischemic Cardiomyopathy

Application and Progress of Combined Mesenchymal Stem Cell Transplantation in the Treatment of Ischemic Cardiomyopathy

Treatment of ischemic cardiomyopathy caused by myocardial infarction (MI) using mesenchymal stem cell (MSC) transplantation is a widely researched field, with promising clinical application. However, the low survival rate of transplanted cells has a severe impact on treatment outcome. Currently, res...

Full description

Bibliographic Details
Main Authors: Ping Hua, Jian-Yang Liu, Jun Tao, Song-Ran Yang
Format: Article
Language:English
Published: Hindawi Limited 2015-01-01
Series:BioMed Research International
Online Access:http://dx.doi.org/10.1155/2015/568502
id doaj-2a8d4c65bfeb42fa8646dbfc1cb14ad2
record_format Article
spelling doaj-2a8d4c65bfeb42fa8646dbfc1cb14ad22020-11-24T23:13:56ZengHindawi LimitedBioMed Research International2314-61332314-61412015-01-01201510.1155/2015/568502568502Application and Progress of Combined Mesenchymal Stem Cell Transplantation in the Treatment of Ischemic CardiomyopathyPing Hua0Jian-Yang Liu1Jun Tao2Song-Ran Yang3Department of Cardiovascular Surgery, Sun Yat-sen Memorial Hospital, Sun Yat-sen University, Guangzhou 510120, ChinaDepartment of Cardiovascular Surgery, Sun Yat-sen Memorial Hospital, Sun Yat-sen University, Guangzhou 510120, ChinaDepartment of Cardiovascular Surgery, Sun Yat-sen Memorial Hospital, Sun Yat-sen University, Guangzhou 510120, ChinaDepartment of Experimental Psychology, University of Oxford, Oxford OX1 3UD, UKTreatment of ischemic cardiomyopathy caused by myocardial infarction (MI) using mesenchymal stem cell (MSC) transplantation is a widely researched field, with promising clinical application. However, the low survival rate of transplanted cells has a severe impact on treatment outcome. Currently, research is focused on investigating the strategy of combining genetic engineering, tissue engineering materials, and drug/hypoxia preconditioning to improve ischemic cardiomyopathy treatment outcome using MSC transplantation treatment (MSCTT). This review discusses the application and progress of these techniques.http://dx.doi.org/10.1155/2015/568502
collection DOAJ
language English
format Article
sources DOAJ
author Ping Hua
Jian-Yang Liu
Jun Tao
Song-Ran Yang
spellingShingle Ping Hua
Jian-Yang Liu
Jun Tao
Song-Ran Yang
Application and Progress of Combined Mesenchymal Stem Cell Transplantation in the Treatment of Ischemic Cardiomyopathy
BioMed Research International
author_facet Ping Hua
Jian-Yang Liu
Jun Tao
Song-Ran Yang
author_sort Ping Hua
title Application and Progress of Combined Mesenchymal Stem Cell Transplantation in the Treatment of Ischemic Cardiomyopathy
title_short Application and Progress of Combined Mesenchymal Stem Cell Transplantation in the Treatment of Ischemic Cardiomyopathy
title_full Application and Progress of Combined Mesenchymal Stem Cell Transplantation in the Treatment of Ischemic Cardiomyopathy
title_fullStr Application and Progress of Combined Mesenchymal Stem Cell Transplantation in the Treatment of Ischemic Cardiomyopathy
title_full_unstemmed Application and Progress of Combined Mesenchymal Stem Cell Transplantation in the Treatment of Ischemic Cardiomyopathy
title_sort application and progress of combined mesenchymal stem cell transplantation in the treatment of ischemic cardiomyopathy
publisher Hindawi Limited
series BioMed Research International
issn 2314-6133
2314-6141
publishDate 2015-01-01
description Treatment of ischemic cardiomyopathy caused by myocardial infarction (MI) using mesenchymal stem cell (MSC) transplantation is a widely researched field, with promising clinical application. However, the low survival rate of transplanted cells has a severe impact on treatment outcome. Currently, research is focused on investigating the strategy of combining genetic engineering, tissue engineering materials, and drug/hypoxia preconditioning to improve ischemic cardiomyopathy treatment outcome using MSC transplantation treatment (MSCTT). This review discusses the application and progress of these techniques.
url http://dx.doi.org/10.1155/2015/568502
work_keys_str_mv AT pinghua applicationandprogressofcombinedmesenchymalstemcelltransplantationinthetreatmentofischemiccardiomyopathy
AT jianyangliu applicationandprogressofcombinedmesenchymalstemcelltransplantationinthetreatmentofischemiccardiomyopathy
AT juntao applicationandprogressofcombinedmesenchymalstemcelltransplantationinthetreatmentofischemiccardiomyopathy
AT songranyang applicationandprogressofcombinedmesenchymalstemcelltransplantationinthetreatmentofischemiccardiomyopathy
_version_ 1725596049098145792

Similar Items