Interaction of growth hormone receptor/binding protein gene disruption and caloric restriction for insulin sensitivity and attenuated aging [v1; ref status: indexed, http://f1000r.es/4fk]

Interaction of growth hormone receptor/binding protein gene disruption and caloric restriction for insulin sensitivity and attenuated aging [v1; ref status: indexed, http://f1000r.es/4fk]

The correlation of physiological sensitivity to insulin (vis-à-vis glycemic regulation) and longevity is extensively established, creating a justifiable gerontological interest on whether insulin sensitivity is causative, or even predictive, of some or all phenotypes of slowed senescence (including...

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Bibliographic Details
Main Authors: Oge Arum, Jamal Saleh, Ravneet Boparai, Jeremy Turner, John Kopchick, Romesh Khardori, Andrzej Bartke
Format: Article
Language:English
Published: F1000 Research Ltd 2014-10-01
Series:F1000Research
Subjects:
Aging
Diabetes & Obesity
Pancreas
Online Access:http://f1000research.com/articles/3-256/v1

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