The Association of the Long Prostate Cancer Expressed PDE4D Transcripts to Poor Patient Outcome Depends on the Tumour’s TMPRSS2-ERG Fusion Status

The Association of the Long Prostate Cancer Expressed PDE4D Transcripts to Poor Patient Outcome Depends on the Tumour’s TMPRSS2-ERG Fusion Status

Objectives. To investigate the added value of assessing transcripts for the long cAMP phosphodiesterase-4D (PDE4D) isoforms, PDE4D5 and PDE4D9, regarding the prognostic power of the ‘CAPRA & PDE4D7’ combination risk model to predict longitudinal postsurgical biological outcomes in prostate cance...

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Bibliographic Details
Main Authors: Dianne van Strijp, Christiane de Witz, Birthe Heitkötter, Sebastian Huss, Martin Bögemann, George S. Baillie, Miles D. Houslay, Chris Bangma, Axel Semjonow, Ralf Hoffmann
Format: Article
Language:English
Published: Hindawi Limited 2019-01-01
Series:Prostate Cancer
Online Access:http://dx.doi.org/10.1155/2019/8107807

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