The effect of cocaine on gastric mucosal PGE2, LTC4 and ulcerations

The association between cocaine use and acute gastroduodenal perforation is known. The effect of cocaine and stress on gastric mucosal ulceration and the levels of prostaglandin E2 (PGE2) and leukotriene C4 (LTC4) was studied in 40 Sprague–Dawley rats. Controls received intraperitoneal (i.p.) saline...

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Bibliographic Details
Main Authors: L. D. G. Angus, T. A. Stein, L. J. Auguste, J. Gintautas, J. Westervelt, L. Wise, G. W. Shaftan
Format: Article
Language:English
Published: Hindawi Limited 1993-01-01
Series:Mediators of Inflammation
Online Access:http://dx.doi.org/10.1155/S096293519300050X