Development of a new and reliable assay for choline kinase using 31P NMR

Choline kinase catalyzes the conversion of choline to phosphocholine (PC) by transferring a phosphate group from adenosine triphosphate (ATP) as the first step in the biosynthetic pathway for the membrane phospholipid phosphatidylcholine, an essential pathway in the Leishmania parasitic protozoan. C...

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Bibliographic Details
Main Authors: Jacob A. Walker, Joshua D. Friesen, Steven J. Peters, Marjorie A. Jones, Jon A. Friesen
Format: Article
Language:English
Published: Elsevier 2019-10-01
Series:Heliyon
Subjects:
TBC
Online Access:http://www.sciencedirect.com/science/article/pii/S2405844019362450