A Quick and Painless Reminder: The Pharmacotherapy of Rheumatoid Arthritis in Primary Practice

A Quick and Painless Reminder: The Pharmacotherapy of Rheumatoid Arthritis in Primary Practice

Rheumatoid arthritis, an auto-immune disorder, is characterized by chronic inflammation of the joints, synovial hyperplasia and bone erosion. These pathological features are promoted by a synovial microenvironment featuring B-cell and T-cell infiltrate, synovial fibroblasts and an intricate network...

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Bibliographic Details
Main Authors: Linda Brand, De Wet Wolmarans, Sarel J. Brand
Format: Article
Language:English
Published: AOSIS 2018-06-01
Series:South African Family Practice
Subjects:
rheumatoid arthritis
pharmacotherapy
Online Access:https://safpj.co.za/index.php/safpj/article/view/4839
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spelling doaj-2a6c1858ce224dcfbe5b84ed8e4140732020-11-25T03:10:52ZengAOSISSouth African Family Practice2078-61902078-62042018-06-01602384210.4102/safp.v60i2.48393827A Quick and Painless Reminder: The Pharmacotherapy of Rheumatoid Arthritis in Primary PracticeLinda Brand0De Wet Wolmarans1Sarel J. Brand2North West-UniversityNorth-West UniversityNorth-West UniversityRheumatoid arthritis, an auto-immune disorder, is characterized by chronic inflammation of the joints, synovial hyperplasia and bone erosion. These pathological features are promoted by a synovial microenvironment featuring B-cell and T-cell infiltrate, synovial fibroblasts and an intricate network of pro-inflammatory cellular messengers – prominent molecular role-players that represent critical targets in the pharmacotherapy of the disease. This review offers a brief overview of the etiopathology of rheumatoid arthritis while focussing on the practical aspects of methotrexate and glucocorticoid use that are of relevance for primary practice.https://safpj.co.za/index.php/safpj/article/view/4839rheumatoid arthritispharmacotherapy
collection DOAJ
language English
format Article
sources DOAJ
author Linda Brand
De Wet Wolmarans
Sarel J. Brand
spellingShingle Linda Brand
De Wet Wolmarans
Sarel J. Brand
A Quick and Painless Reminder: The Pharmacotherapy of Rheumatoid Arthritis in Primary Practice
South African Family Practice
rheumatoid arthritis
pharmacotherapy
author_facet Linda Brand
De Wet Wolmarans
Sarel J. Brand
author_sort Linda Brand
title A Quick and Painless Reminder: The Pharmacotherapy of Rheumatoid Arthritis in Primary Practice
title_short A Quick and Painless Reminder: The Pharmacotherapy of Rheumatoid Arthritis in Primary Practice
title_full A Quick and Painless Reminder: The Pharmacotherapy of Rheumatoid Arthritis in Primary Practice
title_fullStr A Quick and Painless Reminder: The Pharmacotherapy of Rheumatoid Arthritis in Primary Practice
title_full_unstemmed A Quick and Painless Reminder: The Pharmacotherapy of Rheumatoid Arthritis in Primary Practice
title_sort quick and painless reminder: the pharmacotherapy of rheumatoid arthritis in primary practice
publisher AOSIS
series South African Family Practice
issn 2078-6190
2078-6204
publishDate 2018-06-01
description Rheumatoid arthritis, an auto-immune disorder, is characterized by chronic inflammation of the joints, synovial hyperplasia and bone erosion. These pathological features are promoted by a synovial microenvironment featuring B-cell and T-cell infiltrate, synovial fibroblasts and an intricate network of pro-inflammatory cellular messengers – prominent molecular role-players that represent critical targets in the pharmacotherapy of the disease. This review offers a brief overview of the etiopathology of rheumatoid arthritis while focussing on the practical aspects of methotrexate and glucocorticoid use that are of relevance for primary practice.
topic rheumatoid arthritis
pharmacotherapy
url https://safpj.co.za/index.php/safpj/article/view/4839
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