Contraceptives with folate – new possibilities for prophylaxis of fetal congenital abnormalities
Neural tube defects (NTD) are a group of fetal congenital abnormalities which are formed in the first weeks of embryonal development. NTDs are formed when neural tube is not fully closed for the first 28 days after conception, i.e when a woman does not already know that she is pregnant. It is proven...
| Main Authors: | , , |
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| Format: | Article |
| Language: | Russian |
| Published: |
IP Berlin A.V.
2013-02-01
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| Series: | Гинекология |
| Subjects: | |
| Online Access: | https://gynecology.orscience.ru/2079-5831/article/view/28174 |
| Summary: | Neural tube defects (NTD) are a group of fetal congenital abnormalities which are formed in the first weeks of embryonal development. NTDs are formed when neural tube is not fully closed for the first 28 days after conception, i.e when a woman does not already know that she is pregnant. It is proven that risk of NTD is reduced with increase of folate concentration in blood. Recently, two new combined oral contraceptives wit folates. The main aim of the development – prophylaxis of fetal congenital abnormalities which is provided with increased level of folates in organism of women of reproductive age when contraceptives are taken and withdrawn, due to contraceptives enriched with folates. Folates which are contained in combined oral contraceptives with folate, reduce NTD risk if a woman gets pregnant while taking the drug or soon after the drug withdrawal. |
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| ISSN: | 2079-5696 2079-5831 |