6-Shogaol Inhibits Advanced Glycation End-Products-Induced IL-6 and ICAM-1 Expression by Regulating Oxidative Responses in Human Gingival Fibroblasts

6-Shogaol Inhibits Advanced Glycation End-Products-Induced IL-6 and ICAM-1 Expression by Regulating Oxidative Responses in Human Gingival Fibroblasts

Advanced glycation end-products (AGEs) cause diabetes mellitus (DM) complications and accumulate more highly in periodontal tissues of patients with periodontitis and DM. AGEs aggravate periodontitis with DM by increasing the expression of inflammation-related factors in periodontal tissues. 6-Shoga...

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Bibliographic Details
Main Authors: Kohei Nonaka, Mika Bando, Eijiro Sakamoto, Yuji Inagaki, Koji Naruishi, Hiromichi Yumoto, Jun-ichi Kido
Format: Article
Language:English
Published: MDPI AG 2019-10-01
Series:Molecules
Subjects:
advanced glycation end-products
6-shogaol
ros
antioxidant enzyme
il-6
icam-1
human gingival fibroblasts
Online Access:https://www.mdpi.com/1420-3049/24/20/3705

Internet

https://www.mdpi.com/1420-3049/24/20/3705

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