Study of morphological subtypes of major Salivary gland tumors

• Main Author: Suhela R, Vijaya Gattu
• Format: Article
• Language: English
• Published: Prathima Institute of Medical Sciences 2017-12-01
• Series: Perspectives In Medical Research
• Subjects: salivary gland; benign; malignant; neoplasms
• Online Access: http://www.pimr.org.in/suhela_vol5-issue3-2017.PDF

ntroduction: Salivary glands are the site of origin of neoplastic and non neoplastic lesions. Salivary gland tumours account for 2-6% of all the neoplasms of the Head and Neck. Major salivary gland tumors comprise a morphologically diverse group of head and neck tumors. The tumors have variations in their clinical profile related to racial and geographic differences. The tumors also have variations in the treatment types.Salivary gland tumors affect the Parotid 70% of cases followed by Submandibular glands 15%, sublingual glands 1%, minor salivary glands 5-15% . Aims & Objectives: To find out the frequency of various morphological types of major salivary gland neoplasms. To study age, sex,duration and site distribution of different salivary gland lesions. The aim of our study was to describe the frequency of various salivary tumors and characterize them according to age, sex , anatomic location and frequency of the nature, symptoms and type of tumor. A total of 67 surgically resected specimens of salivary gland lesions were analyzed. Materials & Methods This is an observational study which is carried out on 67 patients having major salivary gland tumor in the department of pathology at, SVS Medical college and Hospital, from May 2012 to January 2015. Formalin fixed, paraffin embedded sections stained with hematoxylin and eosin were studied. Results : In this study, most cases occured at 40-50 years of age. Incidence of benign tumors was 72% while that of malignant tumors were 28% overall. Benign tumors of parotid gland were 73.3% and malignant tumors of parotid gland were 26.7% . Benign tumors of submandibular were 57% and malignant tumors of submandibular were 43%. There were no tumors from sublingual or from palate. Conclusion : Parotid gland was the most common site of origin of both benign and malignant tumors. Plemorphic adenoma was the most common benign salivary gland tumor and mucoepidermoid carcinoma was the most frequent malignant neoplasm. Both benign and malignant tumors were more common in males and the common age group affected was from 40-50 years.