Mammalian cells change volume during mitosis.

Mammalian cells change volume during mitosis.

Using single cell-imaging methods we have found that the volume of adherent cells grown in culture decreases as the cells rounds when it enters mitosis. A minimal volume is reached at metaphase. Rapid volume recovery initiates before abscission as cells make the transition from metaphase to cytokine...

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Main Authors: Emmanuel Boucrot, Tomas Kirchhausen
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2008-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC2198941?pdf=render
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spelling doaj-2a542bcc003f407ead5b4f9b0cd283ea2020-11-25T01:53:20ZengPublic Library of Science (PLoS)PLoS ONE1932-62032008-01-0131e147710.1371/journal.pone.0001477Mammalian cells change volume during mitosis.Emmanuel BoucrotTomas KirchhausenUsing single cell-imaging methods we have found that the volume of adherent cells grown in culture decreases as the cells rounds when it enters mitosis. A minimal volume is reached at metaphase. Rapid volume recovery initiates before abscission as cells make the transition from metaphase to cytokinesis. These volume changes are simultaneous with the rapid surface area decrease and recovery observed in mitotic cells [1].http://europepmc.org/articles/PMC2198941?pdf=render
collection DOAJ
language English
format Article
sources DOAJ
author Emmanuel Boucrot
Tomas Kirchhausen
spellingShingle Emmanuel Boucrot
Tomas Kirchhausen
Mammalian cells change volume during mitosis.
PLoS ONE
author_facet Emmanuel Boucrot
Tomas Kirchhausen
author_sort Emmanuel Boucrot
title Mammalian cells change volume during mitosis.
title_short Mammalian cells change volume during mitosis.
title_full Mammalian cells change volume during mitosis.
title_fullStr Mammalian cells change volume during mitosis.
title_full_unstemmed Mammalian cells change volume during mitosis.
title_sort mammalian cells change volume during mitosis.
publisher Public Library of Science (PLoS)
series PLoS ONE
issn 1932-6203
publishDate 2008-01-01
description Using single cell-imaging methods we have found that the volume of adherent cells grown in culture decreases as the cells rounds when it enters mitosis. A minimal volume is reached at metaphase. Rapid volume recovery initiates before abscission as cells make the transition from metaphase to cytokinesis. These volume changes are simultaneous with the rapid surface area decrease and recovery observed in mitotic cells [1].
url http://europepmc.org/articles/PMC2198941?pdf=render
work_keys_str_mv AT emmanuelboucrot mammaliancellschangevolumeduringmitosis
AT tomaskirchhausen mammaliancellschangevolumeduringmitosis
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