Embryonic Stem Cell-Derived Glial Precursors as a Vehicle for Sulfamidase Production in the MPS-IIIA Mouse Brain

Embryonic Stem Cell-Derived Glial Precursors as a Vehicle for Sulfamidase Production in the MPS-IIIA Mouse Brain

Pluripotent stem cells, including human embryonic stem cells and induced pluripotent stem cells, have generated much excitement about their prospects for use in cell transplantation therapies. This is largely attributable to their virtually unlimited growth potential, their ability to be precisely g...

Full description

Bibliographic Details
Main Authors:	Aaron J. Robinson, Guoying Zhao, Joy Rathjen, Peter D. Rathjen, Rhonda G. Hutchinson, Helen J. Eyre, Kim M. Hemsley, John J. Hopwood
Format:	Article
Language:	English
Published:	SAGE Publishing 2010-08-01
Series:	Cell Transplantation
Online Access:	https://doi.org/10.3727/096368910X498944

Similar Items

Enhancing the Therapeutic Potential of Sulfamidase for the Treatment of Mucopolysaccharidosis IIIA
by: Nicolina Cristina Sorrentino, et al.
Published: (2019-12-01)

Formation of Neural Precursor Cell Populations by Differentiation of Embryonic Stem Cells In Vitro
by: Joy Rathjen, et al.
Published: (2002-01-01)

Enzyme replacement reduces neuropathology in MPS IIIA dogs
by: Allison C. Crawley, et al.
Published: (2011-08-01)

Intravenous delivery of a chemically modified sulfamidase efficiently reduces heparan sulfate storage and brain pathology in mucopolysaccharidosis IIIA mice
by: Susanne Gustavsson, et al.
Published: (2019-12-01)

Retinal Degeneration in MPS-IIIA Mouse Model
by: Daniela Intartaglia, et al.
Published: (2020-03-01)

Crystal Structures of a Bacterial Isocitrate Dehydrogenase and the Human Sulfamidase
by: Sidhu, Navdeep Singh
Published: (2015)

AAVrh10 Vector Corrects Disease Pathology in MPS IIIA Mice and Achieves Widespread Distribution of SGSH in Large Animal Brains
by: Michaël Hocquemiller, et al.
Published: (2020-06-01)

Schwann Cell Precursors; Multipotent Glial Cells in Embryonic Nerves
by: Kristjan R. Jessen, et al.
Published: (2019-03-01)

Characterization of glial-restricted precursors from rhesus monkey embryonic stem cells
by: Chen Hongwei, et al.
Published: (2015-01-01)

An Engineered <i>sgsh</i> Mutant Zebrafish Recapitulates Molecular and Behavioural Pathobiology of Sanfilippo Syndrome A/MPS IIIA
by: Alon M. Douek, et al.
Published: (2021-05-01)

Functional correction of neurological and somatic disorders at later stages of disease in MPS IIIA mice by systemic scAAV9-hSGSH gene delivery
by: Haiyan Fu, et al.
Published: (2016-01-01)

Distribution of Heparan Sulfate Oligosaccharides in Murine Mucopolysaccharidosis Type IIIA
by: Kerryn Mason, et al.
Published: (2014-12-01)

Whole Body and CNS Biodistribution of rhHNS in Cynomolgus Monkeys after Intrathecal Lumbar Administration: Treatment Implications for Patients with MPS IIIA
by: Jou-Ku Chung, et al.
Published: (2017-12-01)

A requirement for FGF signalling in the formation of primitive streak-like intermediates from primitive ectoderm in culture.
by: Zhiqiang Zheng, et al.
Published: (2010-09-01)

Expression profiling of human glial precursors
by: Chesnut Jonathan D, et al.
Published: (2008-10-01)

An investigation of the system Cr(III)/Cr(II) by digital polarography, at dirrerent Cr(III) concentrations, at varying pH, and in different supporting electrolytes
by: Rathjen, Nancy
Published: (1969)

Hypothesis of a Non-SNARE-Function of Syntaxin-5
by: Rathjen, Stefan
Published: (2017)

Findbuch des Bestandes Abt. 13: Obergericht zu Gottorf 1713-1834
by: Rathjen, Jörg
Published: (2017)

Findbuch der Bestände Abt. 18 und Abt. 19: Generalsuperintendent für Schleswig und Generalsuperintendent für Holstein
by: Rathjen, Jörg
Published: (2016)

Findbuch des Bestandes Abt. 22: Herzöge von Schleswig-Holstein-Sonderburg-Augustenburg/
by: Rathjen, Jörg
Published: (2012)

Findbuch des Bestandes Abteilung 79: Ministerium für das Herzogtum Schleswig zu Kopenhagen 1851-1864
by: Rathjen, Jörg
Published: (2008)

Findbuch der Bestände Abt. 80 und Abt. 56: Ministerium für die Herzogtümer Holstein und Lauenburg zu Kopenhagen 1852-1864 und Holsteinische Regierung zu Kopenhagen bzw. Plön 1862-1864
by: Rathjen, Jörg
Published: (2010)

Findbuch des Bestandes Abt. 49. Schleswig-Holsteinische Regierung auf Gottorf 1834-1851
by: Rathjen, Jörg
Published: (2017)

Findbuch der Bestände Abt. 51 bis Abt. 55: Abt. 51 Regierungen der Herzogtümer während der Erhebung 1848-1851 / Abt. 52 Dänische Immediatkommission zur gemeinsamen Regierung der Herzogtümer in Sonderburg 1848-1849 / Abt. 53 Landesverwaltung für das Herzogtum Schleswig 1849-1851 und Dänischer Regierungskommissar 1850-1851 /Abt. 54 Oberste Zivilbehörde für das Herzogtum Holstein in Kiel 1851-1852 /
by: Rathjen, Jörg
Published: (2010)

Findbuch der Bestände Abt. 57 bis Abt. 62: Preußisch-österreichische Übergangsbehörden 1863-1868/Abt. 57: Bundeskommissare für die Herzogtümer Holstein und Lauenburg 1863-1864; Abt. 58.1: Österreichisch-preußische Oberste Zivilbehörde für das Herzogtum Schleswig 1864; Abt. 58.2: Österreichisch-preußische Oberste Zivilbehörde für die Herzogtümer Schleswig, Holstein und Lauenburg 1864-1865; Abt. 59.
by: Rathjen, Jörg
Published: (2012)

Vom Sinn und Unsinn aller Allegorie : Das Versteckspiel mit dem Leser im Romanwerk Martin Mosebachs = The sense and nonsense of allegory : the game of hide and seek with the reader in the novels of Martin Mosebach
by: Rathjen, Kirsten
Published: (2011)

Experimentelle Wärme-, Stoffübergangsuntersuchungen an einem rotierenden Kühlkanalmodell mit Rippen
by: Rathjen, Lars
Published: (2004)

Impact of chemical modification of sulfamidase on distribution to brain interstitial fluid and to CSF after an intravenous administration in awake, freely-moving rats
by: Juliette Janson, et al.
Published: (2020-03-01)

Differences in MPS I and MPS II Disease Manifestations
by: Christiane S. Hampe, et al.
Published: (2021-07-01)

Embryonic microglia influence developing hypothalamic glial populations
by: Candace M. Marsters, et al.
Published: (2020-05-01)

Metaboloepigenetic Regulation of Pluripotent Stem Cells
by: Alexandra J. Harvey, et al.
Published: (2016-01-01)

Elektrophysiologische Cue-Reaktivität und Aufmerksamkeitsverzerrung bei alkoholabhängigen Patienten
by: Rathjen, Hella Elisabeth
Published: (2005)

Non-linear computer models of field-effect transistors
by: Rathjen, Arthur David
Published: (2012)

Expression signals in retro-elements
by: Rathjen, Peter David
Published: (1988)

Genetic differentiation in Phaseolus vulgaris L
by: Rathjen, Anthony John
Published: (1966)

Ars legendi-Preis des Stifterverbandes für exzellente Hochschullehre 2006 []
by: Rathjen, Jan, et al.
Published: (2006-05-01)

Exposing industry-driven retail incentive programs that undermine tobacco tax policies
by: Heidi Rathjen, et al.
Published: (2018-03-01)

MPS i molnet
by: Johansson, Björn, et al.
Published: (2014)

The effect of mechanical and shear forces on embryonic stem cells
by: Hemsley, A. L.
Published: (2014)

Differentiation of Human Embryonic Stem Cells into Neuron, Cholinergic, and Glial Cells
by: Kimia Hosseini, et al.
Published: (2020-01-01)