Competition for IL-2 between regulatory and effector T cells to chisel immune responses

Competition for IL-2 between regulatory and effector T cells to chisel immune responses

In this review we discuss how the competition for cytokines between different cells of the immune system can shape the system wide immune response. We focus on interleukin-2 (IL-2) secretion by activated effector T cells (Teff) and on the competition for IL-2 consumption between Teff and regulatory...

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Bibliographic Details
Main Authors: Thomas eHöfer, Oleg eKrichevsky, Grégoire eAltan-Bonnet
Format: Article
Language:English
Published: Frontiers Media S.A. 2012-09-01
Series:Frontiers in Immunology
Subjects:
computational modeling
regulatory T cells
IL-2
Cytokine competition
Systems Immunology
Online Access:http://journal.frontiersin.org/Journal/10.3389/fimmu.2012.00268/full

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