miR-152 Attenuates the Severity of Lupus Nephritis Through the Downregulation of Macrophage Migration Inhibitory Factor (MIF)-Induced Expression of COL1A1

miR-152 Attenuates the Severity of Lupus Nephritis Through the Downregulation of Macrophage Migration Inhibitory Factor (MIF)-Induced Expression of COL1A1

Background: The role of miR-152 in lupus nephritis has not been elucidated. The aim of this study was to investigate the role of miR-152 in the pathogenesis of lupus nephritis (LN).Methods: miR-152 expression was detected using RT-PCR in LN tissue and normal controls. The miR-152 expression was comp...

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Bibliographic Details
Main Authors: Jiayi Zheng, Ruru Guo, Yuanjia Tang, Qiong Fu, Jie Chen, Lingling Wu, Lin Leng, Richard Bucala, Yang Song, Liangjing Lu
Format: Article
Language:English
Published: Frontiers Media S.A. 2019-02-01
Series:Frontiers in Immunology
Subjects:
miR-152
macrophage migration inhibitory Factor (MIF)
COL1A1
lupus nephritis
chronicity index
Online Access:https://www.frontiersin.org/article/10.3389/fimmu.2019.00158/full

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