Impairing of Serotonin Synthesis by P-Chlorphenylanine Prevents the Forgetting of Contextual Memory After Reminder and the Protein Synthesis Inhibition

Impairing of Serotonin Synthesis by P-Chlorphenylanine Prevents the Forgetting of Contextual Memory After Reminder and the Protein Synthesis Inhibition

HIGHLIGHTSThe injection of p-chlorophenylalanine, specific blocker of 5-HT synthesis 3 days before reminder with anisomycin administration prevented forgetting.It is known that the reminder cause reactivation of the long-term memory and it leads to reconsolidation of memory. We showed earlier that t...

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Bibliographic Details
Main Authors: Irina B. Deryabina, Lyudmila N. Muranova, Vyatcheslav V. Andrianov, Khalil L. Gainutdinov
Format: Article
Language:English
Published: Frontiers Media S.A. 2018-06-01
Series:Frontiers in Pharmacology
Subjects:
serotonin (5-HT)
p-CPA
consolidation
contextual memory
reconsolidation
anisomycin (AN)
Online Access:https://www.frontiersin.org/article/10.3389/fphar.2018.00607/full

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