Signatures of T cells as correlates of immunity to Francisella tularensis.

Signatures of T cells as correlates of immunity to Francisella tularensis.

Tularemia or vaccination with the live vaccine strain (LVS) of Francisella tularensis confers long-lived cell-mediated immunity. We hypothesized that this immunity depends on polyfunctional memory T cells, i.e., CD4(+) and/or CD8(+) T cells with the capability to simultaneously express several funct...

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Bibliographic Details
Main Authors: Kjell Eneslätt, Monica Normark, Rafael Björk, Cecilia Rietz, Carl Zingmark, Lawrence A Wolfraim, Svenja Stöven, Anders Sjöstedt
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2012-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3295757?pdf=render

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