A Population Pharmacokinetic Model of Intravenous Dexmedetomidine for Mechanically Ventilated Children after Neurosurgery

A Population Pharmacokinetic Model of Intravenous Dexmedetomidine for Mechanically Ventilated Children after Neurosurgery

Dexmedetomidine is a selective alpha-2 adrenergic agonist with concurrent sedative and analgesic effects, and it is being increasingly used in pediatric anesthesia and intensive care. This study aimed to investigate the pharmacokinetics of intravenous dexmedetomidine in mechanically ventilated child...

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Bibliographic Details
Main Authors: In-Kyung Song, SoJeong Yi, Hyeong-Seok Lim, Ji-Hyun Lee, Eun-Hee Kim, Joo-Youn Cho, Min-Chang Kim, Jin-Tae Kim, Hee-Soo Kim
Format: Article
Language:English
Published: MDPI AG 2019-10-01
Series:Journal of Clinical Medicine
Subjects:
child
deep sedation
dexmedetomidine
intensive care units
pharmacokinetics
preschool child
Online Access:https://www.mdpi.com/2077-0383/8/10/1563

Internet

https://www.mdpi.com/2077-0383/8/10/1563

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