Otimização do processo de extração e isolamento do antimalárico artemisinina a partir de Artemisia annua L. Optimization of the extraction and isolation of the antimalarial drug artemisinin from Artemisia annua L.

• Main Authors: Rodney Alexandre Ferreira Rodrigues, Mary Ann Foglio, Sinésio Boaventura Júnior, Adriana da Silva Santos, Vera Lúcia Garcia Rehder
• Format: Article
• Language: English
• Published: Sociedade Brasileira de Química 2006-04-01
• Series: Química Nova
• Subjects: malaria; artemisinin production; Artemisia annua L
• Online Access: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0100-40422006000200030
• ISSN: 0100-4042; 1678-7064

<abstract language="eng">Malaria is still one of the major diseases in the world, causing physical and economic problems in tropical regions. Artemisinin (Qinghaosu), a natural compound identified in Artemisia annua L. , is an effective drug mainly against cerebral malaria. The action of this drug is immediate and parasitaemia in the treatment of drug-resistant malaria is rapidily reduced, justifying the industrial production of artemisinin. This article focuses on the industrial production of this potent antimalarial drug, including strategies for enhancing yield using inexpensive and easy steps.