A novel medium-throughput biological assay system for HTLV-1 infectivity and drug discovery

A novel medium-throughput biological assay system for HTLV-1 infectivity and drug discovery

Objective(s): Here, a reporter cell line containing two reporter vectors were developed, in order to monitor the Human T-Lymphotropic Virus type1(HTLV-1) infectivity and the cell viability simultaneously. Materials and Methods: The reporter cell line was constructed by stably transfected baby hamste...

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Bibliographic Details
Main Authors: Mojtaba Fattahi Abdizadeh, Manoochehr Makvandi, Alireza Samarbafzadeh, Kayhan Azadmanesh
Format: Article
Language:English
Published: Mashhad University of Medical Sciences 2017-10-01
Series:Iranian Journal of Basic Medical Sciences
Subjects:
Biological Assay
Drug screening
HTLV-1
Hut102
Luciferase
Reporter gene
Online Access:http://ijbms.mums.ac.ir/article_9417_04ec4c75273a85322aff84c4fc11522d.pdf

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