A c-di-GMP effector system controls cell adhesion by inside-out signaling and surface protein cleavage.

A c-di-GMP effector system controls cell adhesion by inside-out signaling and surface protein cleavage.

In Pseudomonas fluorescens Pf0-1 the availability of inorganic phosphate (Pi) is an environmental signal that controls biofilm formation through a cyclic dimeric GMP (c-di-GMP) signaling pathway. In low Pi conditions, a c-di-GMP phosphodiesterase (PDE) RapA is expressed, depleting cellular c-di-GMP...

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Bibliographic Details
Main Authors: Peter D Newell, Chelsea D Boyd, Holger Sondermann, George A O'Toole
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2011-02-01
Series:PLoS Biology
Online Access:http://europepmc.org/articles/PMC3032545?pdf=render

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