The Expression of the Ubiquitin Ligase SIAH2 (Seven In Absentia Homolog 2) Is Increased in Human Lung Cancer.

OBJECTIVES:Lung cancer is the leading cause of cancer-related deaths worldwide. Overall 5-year survival has shown little improvement over the last decades. Seven in absentia homolog (SIAH) proteins are E3 ubiquitin ligases that mediate proteasomal protein degradation by poly-ubiquitination. Even tho...

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Bibliographic Details
Main Authors: Paula Moreno, Maribel Lara-Chica, Rafael Soler-Torronteras, Teresa Caro, Manuel Medina, Antonio Álvarez, Ángel Salvatierra, Eduardo Muñoz, Marco A Calzado
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2015-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC4651316?pdf=render

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