Congenital cystic adenomatoid malformation presentation of 11 cases and literature review

• Main Authors: Jozef Kobos, Damian Młynarski, Bartosz Bogusz, Wojciech Górecki
• Format: Article
• Language: English
• Published: Termedia Publishing House 2021-02-01
• Series: Polish Journal of Pathology
• Subjects: congenital cystic adenomatoid malformation; ccam; lung lesion; respiratory tract disorder.
• Online Access: https://www.termedia.pl/Congenital-cystic-adenomatoid-malformation-presentation-of-11-cases-and-literature-review,55,43324,1,1.html
• ISSN: 1233-9687; 2084-9869

The aim of the study was to present cases of congenital cystic adenomatoid malformation (CCAM) in terms of pathological features, gender and site distribution as well as to compare the results with Stocker’s classification. A retrospective review was performed on eleven cases of CCAM obtained in 4-years period (2015-2019) in University Children’s Hospital in Krakow, in Poland. The cases for this study were 7 boys and 4 girls (64% vs. 36%). Patients age at surgery ranged from 4 days to 10 months. 6 cases involved the left lung (55%) whereas the right lung was involved in 5 cases (45%). Histopathological examination showed congenital cystic adenomatoid malformation type I in 7 cases (64%), type II in 3 cases (27%) and type III in 1 case (9%). No congenital cystic adenomatoid malformation type 0 nor IV was diagnosed. Data obtained from this study correspond to Stocker’s classification, showing that the most common CCAM types are those associated with good prognosis. Histopathological features should always confirm the nature of the lesion, that is initially suspected in the imaging examination.