A simple PCR method for rapid genotype analysis of the TH-MYCN transgenic mouse.

BACKGROUND: The TH-MYCN transgenic mouse is the most widely used murine model of human neuroblastoma, in which a human MYCN oncogene is targeted to neuroectodermal cells of developing mice under the influence of the rat tyrosine hydroxylase promoter. So far, homozygous transgenic mice have been iden...

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Bibliographic Details
Main Authors: Seiki Haraguchi, Akira Nakagawara
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2009-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC2731925?pdf=render

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