Suppression of hypoxia and inflammatory pathways by Phyllanthus niruri extract inhibits angiogenesis in DMBA-induced breast cancer mice

Suppression of hypoxia and inflammatory pathways by Phyllanthus niruri extract inhibits angiogenesis in DMBA-induced breast cancer mice

Background and purpose: Angiogenesis has been one of the hallmarks of cancer. In recent years, Phyllanthus niruri extract (PNE) was reported to inhibit angiogenesis by decreasing the levels of vascular endothelial growth factor (VEGF) and hypoxia-inducible factor-1a (HIF-1a) in breast cancer. Howeve...

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Bibliographic Details
Main Authors: Abu Hanifah Ramadhani, Ahmad Hafidul Ahkam, Aditya Ragil Suharto, Yoga Dwi Jatmiko, Hideo Tsuboi, Muhaimin Rifa'i
Format: Article
Language:English
Published: Wolters Kluwer Medknow Publications 2021-01-01
Series:Research in Pharmaceutical Sciences
Subjects:
angiogenesis; breast cancer; dmba; inflammation; phyllanthus niruri
Online Access:http://www.rpsjournal.net/article.asp?issn=1735-5362;year=2021;volume=16;issue=2;spage=217;epage=226;aulast=Ramadhani

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http://www.rpsjournal.net/article.asp?issn=1735-5362;year=2021;volume=16;issue=2;spage=217;epage=226;aulast=Ramadhani

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