Identification of key genes controlling breast cancer stem cell characteristics via stemness indices analysis

Abstract Background With the gradual unveiling of tumour heterogeneity, cancer stem cells (CSCs) are now being considered the initial component of tumour initiation. However, the mechanisms of the growth and maintenance of breast cancer (BRCA) stem cells are still unknown. Methods To explore the cru...

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Bibliographic Details
Main Authors: Jianying Pei, Yanxia Wang, Yan Li
Format: Article
Language:English
Published: BMC 2020-02-01
Series:Journal of Translational Medicine
Subjects:
Online Access:https://doi.org/10.1186/s12967-020-02260-9