Approaches to managing cytopenias in Autoimmune Lymphoproliferative Syndrome (ALPS).
Autoimmune Lymphoproliferative Syndrome (ALPS) is a rare disorder frequently due to mutations in FAS (TNFRSF6) gene. Unlike most of the self limiting autoimmune cytopenias sporadically seen in childhood, multi lineage cytopenias due to ALPS are often refractory as their inherited genetic defect is n...
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| Format: | Article |
| Language: | English |
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Frontiers Media S.A.
2015-07-01
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| Series: | Frontiers in Pediatrics |
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| Online Access: | http://journal.frontiersin.org/Journal/10.3389/fped.2015.00065/full |