Three step synthesis of single diastereoisomers of the vicinal trifluoro motif

A three step route to single diastereoisomers of the vicinal trifluoromethyl motif is described. The route starts from either syn- or anti-α,β-epoxy alcohols and takes a direct approach in that each of the three steps introduces a fluorine atom in a regio- and stereo-specific manner. Starting from e...

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Bibliographic Details
Main Authors: Vincent A. Brunet, Alexandra M. Z. Slawin, David O'Hagan
Format: Article
Language:English
Published: Beilstein-Institut 2009-11-01
Series:Beilstein Journal of Organic Chemistry
Subjects:
Online Access:https://doi.org/10.3762/bjoc.5.61