Gamma oscillations in somatosensory cortex recruit prefrontal and descending serotonergic pathways in aversion and nociception

Gamma oscillations in somatosensory cortex recruit prefrontal and descending serotonergic pathways in aversion and nociception

Gamma oscillations in somatosensory areas in humans correlate with pain perception and pain stimulus intensity, but could also reflect cognitive processes such as attention. Here the authors provide evidence in mice that these oscillations causally contribute to pain perception.

Bibliographic Details
Main Authors: Linette Liqi Tan, Manfred Josef Oswald, Céline Heinl, Oscar Andrés Retana Romero, Sanjeev Kumar Kaushalya, Hannah Monyer, Rohini Kuner
Format: Article
Language:English
Published: Nature Publishing Group 2019-02-01
Series:Nature Communications
Online Access:https://doi.org/10.1038/s41467-019-08873-z
id doaj-29b14a87920b440ea5bca332cadd7081
record_format Article
spelling doaj-29b14a87920b440ea5bca332cadd70812021-05-11T12:12:29ZengNature Publishing GroupNature Communications2041-17232019-02-0110111710.1038/s41467-019-08873-zGamma oscillations in somatosensory cortex recruit prefrontal and descending serotonergic pathways in aversion and nociceptionLinette Liqi Tan0Manfred Josef Oswald1Céline Heinl2Oscar Andrés Retana Romero3Sanjeev Kumar Kaushalya4Hannah Monyer5Rohini Kuner6Pharmacology Institute, Medical Faculty HeidelbergPharmacology Institute, Medical Faculty HeidelbergPharmacology Institute, Medical Faculty HeidelbergPharmacology Institute, Medical Faculty HeidelbergPharmacology Institute, Medical Faculty HeidelbergDepartment of Clinical Neurobiology, Medical Faculty Heidelberg and German Cancer Research CenterPharmacology Institute, Medical Faculty HeidelbergGamma oscillations in somatosensory areas in humans correlate with pain perception and pain stimulus intensity, but could also reflect cognitive processes such as attention. Here the authors provide evidence in mice that these oscillations causally contribute to pain perception.https://doi.org/10.1038/s41467-019-08873-z
collection DOAJ
language English
format Article
sources DOAJ
author Linette Liqi Tan
Manfred Josef Oswald
Céline Heinl
Oscar Andrés Retana Romero
Sanjeev Kumar Kaushalya
Hannah Monyer
Rohini Kuner
spellingShingle Linette Liqi Tan
Manfred Josef Oswald
Céline Heinl
Oscar Andrés Retana Romero
Sanjeev Kumar Kaushalya
Hannah Monyer
Rohini Kuner
Gamma oscillations in somatosensory cortex recruit prefrontal and descending serotonergic pathways in aversion and nociception
Nature Communications
author_facet Linette Liqi Tan
Manfred Josef Oswald
Céline Heinl
Oscar Andrés Retana Romero
Sanjeev Kumar Kaushalya
Hannah Monyer
Rohini Kuner
author_sort Linette Liqi Tan
title Gamma oscillations in somatosensory cortex recruit prefrontal and descending serotonergic pathways in aversion and nociception
title_short Gamma oscillations in somatosensory cortex recruit prefrontal and descending serotonergic pathways in aversion and nociception
title_full Gamma oscillations in somatosensory cortex recruit prefrontal and descending serotonergic pathways in aversion and nociception
title_fullStr Gamma oscillations in somatosensory cortex recruit prefrontal and descending serotonergic pathways in aversion and nociception
title_full_unstemmed Gamma oscillations in somatosensory cortex recruit prefrontal and descending serotonergic pathways in aversion and nociception
title_sort gamma oscillations in somatosensory cortex recruit prefrontal and descending serotonergic pathways in aversion and nociception
publisher Nature Publishing Group
series Nature Communications
issn 2041-1723
publishDate 2019-02-01
description Gamma oscillations in somatosensory areas in humans correlate with pain perception and pain stimulus intensity, but could also reflect cognitive processes such as attention. Here the authors provide evidence in mice that these oscillations causally contribute to pain perception.
url https://doi.org/10.1038/s41467-019-08873-z
work_keys_str_mv AT linetteliqitan gammaoscillationsinsomatosensorycortexrecruitprefrontalanddescendingserotonergicpathwaysinaversionandnociception
AT manfredjosefoswald gammaoscillationsinsomatosensorycortexrecruitprefrontalanddescendingserotonergicpathwaysinaversionandnociception
AT celineheinl gammaoscillationsinsomatosensorycortexrecruitprefrontalanddescendingserotonergicpathwaysinaversionandnociception
AT oscarandresretanaromero gammaoscillationsinsomatosensorycortexrecruitprefrontalanddescendingserotonergicpathwaysinaversionandnociception
AT sanjeevkumarkaushalya gammaoscillationsinsomatosensorycortexrecruitprefrontalanddescendingserotonergicpathwaysinaversionandnociception
AT hannahmonyer gammaoscillationsinsomatosensorycortexrecruitprefrontalanddescendingserotonergicpathwaysinaversionandnociception
AT rohinikuner gammaoscillationsinsomatosensorycortexrecruitprefrontalanddescendingserotonergicpathwaysinaversionandnociception
_version_ 1721445239649992704

Similar Items