Endothelial nitric oxide synthase regulates white matter changes via the BDNF/TrkB pathway after stroke in mice.

Endothelial nitric oxide synthase regulates white matter changes via the BDNF/TrkB pathway after stroke in mice.

Stroke induced white matter (WM) damage is associated with neurological functional deficits, but the underlying mechanisms are not well understood. In this study, we investigate whether endothelial nitric oxide synthase (eNOS) affects WM-damage post-stroke. Adult male wild-type (WT) and eNOS knockou...

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Bibliographic Details
Main Authors: Xu Cui, Michael Chopp, Alex Zacharek, Ruizhuo Ning, Xiaoshuang Ding, Cynthia Roberts, Jieli Chen
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2013-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3827451?pdf=render

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