An immunostimulatory dual-functional nanocarrier that improves cancer immunochemotherapy

The use of immunostimulatory agents to enhance the efficacy of chemotherapy is a promising strategy in cancer therapy. Here, the authors report on a micellar nanoparticle that can effectively co-deliver chemo- and immunotherapeutics, resulting in an improved in vivoantitumour response.

Bibliographic Details
Main Authors:	Yichao Chen, Rui Xia, Yixian Huang, Wenchen Zhao, Jiang Li, Xiaolan Zhang, Pengcheng Wang, Raman Venkataramanan, Jie Fan, Wen Xie, Xiaochao Ma, Binfeng Lu, Song Li
Format:	Article
Language:	English
Published:	Nature Publishing Group 2016-11-01
Series:	Nature Communications
Online Access:	https://doi.org/10.1038/ncomms13443

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spelling	doaj-29a44d8346d543108c6b74a692465e632021-05-11T10:46:21ZengNature Publishing GroupNature Communications2041-17232016-11-017111210.1038/ncomms13443An immunostimulatory dual-functional nanocarrier that improves cancer immunochemotherapyYichao Chen0Rui Xia1Yixian Huang2Wenchen Zhao3Jiang Li4Xiaolan Zhang5Pengcheng Wang6Raman Venkataramanan7Jie Fan8Wen Xie9Xiaochao Ma10Binfeng Lu11Song Li12Center for Pharmacogenetics, School of Pharmacy, University of PittsburghDepartment of Immunology, School of Medicine, University of PittsburghCenter for Pharmacogenetics, School of Pharmacy, University of PittsburghDepartment of Pharmaceutical Sciences, School of Pharmacy, University of PittsburghCenter for Pharmacogenetics, School of Pharmacy, University of PittsburghCenter for Pharmacogenetics, School of Pharmacy, University of PittsburghCenter for Pharmacogenetics, School of Pharmacy, University of PittsburghDepartment of Pharmaceutical Sciences, School of Pharmacy, University of PittsburghDepartment of Surgery, School of Medicine, University of PittsburghCenter for Pharmacogenetics, School of Pharmacy, University of PittsburghCenter for Pharmacogenetics, School of Pharmacy, University of PittsburghUniversity of Pittsburgh Cancer Institute, University of PittsburghCenter for Pharmacogenetics, School of Pharmacy, University of PittsburghThe use of immunostimulatory agents to enhance the efficacy of chemotherapy is a promising strategy in cancer therapy. Here, the authors report on a micellar nanoparticle that can effectively co-deliver chemo- and immunotherapeutics, resulting in an improved in vivoantitumour response.https://doi.org/10.1038/ncomms13443
collection	DOAJ
language	English
format	Article
sources	DOAJ
author	Yichao Chen Rui Xia Yixian Huang Wenchen Zhao Jiang Li Xiaolan Zhang Pengcheng Wang Raman Venkataramanan Jie Fan Wen Xie Xiaochao Ma Binfeng Lu Song Li
spellingShingle	Yichao Chen Rui Xia Yixian Huang Wenchen Zhao Jiang Li Xiaolan Zhang Pengcheng Wang Raman Venkataramanan Jie Fan Wen Xie Xiaochao Ma Binfeng Lu Song Li An immunostimulatory dual-functional nanocarrier that improves cancer immunochemotherapy Nature Communications
author_facet	Yichao Chen Rui Xia Yixian Huang Wenchen Zhao Jiang Li Xiaolan Zhang Pengcheng Wang Raman Venkataramanan Jie Fan Wen Xie Xiaochao Ma Binfeng Lu Song Li
author_sort	Yichao Chen
title	An immunostimulatory dual-functional nanocarrier that improves cancer immunochemotherapy
title_short	An immunostimulatory dual-functional nanocarrier that improves cancer immunochemotherapy
title_full	An immunostimulatory dual-functional nanocarrier that improves cancer immunochemotherapy
title_fullStr	An immunostimulatory dual-functional nanocarrier that improves cancer immunochemotherapy
title_full_unstemmed	An immunostimulatory dual-functional nanocarrier that improves cancer immunochemotherapy
title_sort	immunostimulatory dual-functional nanocarrier that improves cancer immunochemotherapy
publisher	Nature Publishing Group
series	Nature Communications
issn	2041-1723
publishDate	2016-11-01
description	The use of immunostimulatory agents to enhance the efficacy of chemotherapy is a promising strategy in cancer therapy. Here, the authors report on a micellar nanoparticle that can effectively co-deliver chemo- and immunotherapeutics, resulting in an improved in vivoantitumour response.
url	https://doi.org/10.1038/ncomms13443
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An immunostimulatory dual-functional nanocarrier that improves cancer immunochemotherapy

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