Rapid inverse planning for pressure-driven drug infusions in the brain.

Infusing drugs directly into the brain is advantageous to oral or intravenous delivery for large molecules or drugs requiring high local concentrations with low off-target exposure. However, surgeons manually planning the cannula position for drug delivery in the brain face a challenging three-dimen...

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Bibliographic Details
Main Authors: Kathryn H Rosenbluth, Alastair J Martin, Stephan Mittermeyer, Jan Eschermann, Peter J Dickinson, Krystof S Bankiewicz
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2013-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3574124?pdf=render