Current possibilities for treatment for hepatitis C virus-induced cryoglobulinemic vasculitis and B-cell lymphoma

• Main Authors: T M Ignatova, N A Mukhin
• Format: Article
• Language: Russian
• Published: "Consilium Medicum" Publishing house 2012-11-01
• Series: Терапевтический архив
• Subjects: cryoglobulinemic vasculitis; b-cell lymphomas; hepatitis c virus; antiviral treatment; rituximab
• Online Access: https://ter-arkhiv.ru/0040-3660/article/view/31159

The paper presents a detailed review of the data available in the literature on the treatment of cryoglobulinemic vasculitis and some forms of B-cell non-Hodgkin lymphoma caused by hepatitis C virus. It shows treatment successes associated with the use of current combined antiviral therapy (interferon-α and ribavirin) and its combination with anti-CD20 monoclonal antibodies (rituximab). The combined therapy with rituximab and antiviral drugs allows a radical improvement of prognosis in nearly 50% of patients. Remaining treatment problems and new drug prospects are discussed.