Effect of arginase II on L-arginine depletion and cell growth in murine cell lines of renal cell carcinoma

Effect of arginase II on L-arginine depletion and cell growth in murine cell lines of renal cell carcinoma

<p>Abstract</p> <p>Background</p> <p>L-arginine is the common substrate for the two isoforms of arginase. Arginase I, highly expressed in the liver and arginase II mainly expressed in the kidney. Arginase I-producing myeloid derived suppressor cells have been shown to i...

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Bibliographic Details
Main Authors: Patterson John R, Metoyer Toye, Caldas Yupanqui A, Vonderhaar Derek J, Tate David J, Aviles Diego H, Zea Arnold H
Format: Article
Language:English
Published: BMC 2008-09-01
Series:Journal of Hematology & Oncology
Online Access:http://www.jhoonline.org/content/1/1/14

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