Porcine Deltacoronavirus Accessory Protein NS7a Antagonizes IFN-β Production by Competing With TRAF3 and IRF3 for Binding to IKKε

Porcine Deltacoronavirus Accessory Protein NS7a Antagonizes IFN-β Production by Competing With TRAF3 and IRF3 for Binding to IKKε

As an emerging swine enteropathogenic coronavirus, porcine deltacoronavirus (PDCoV) not only causes serious diarrhea in suckling piglets but also possesses the potential for cross-species transmission, which has sparked growing interest when studying this emerging virus. We previously identified a n...

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Bibliographic Details
Main Authors: Puxian Fang, Liurong Fang, Sijin Xia, Jie Ren, Jiansong Zhang, Dongcheng Bai, Yanrong Zhou, Guiqing Peng, Shuhong Zhao, Shaobo Xiao
Format: Article
Language:English
Published: Frontiers Media S.A. 2020-06-01
Series:Frontiers in Cellular and Infection Microbiology
Subjects:
porcine deltacoronavirus
accessory protein
NS7a
immune evasion
interferon
Online Access:https://www.frontiersin.org/article/10.3389/fcimb.2020.00257/full

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