A semantics-oriented computational approach to investigate microRNA regulation on glucocorticoid resistance in pediatric acute lymphoblastic leukemia
Abstract Background Acute lymphoblastic leukemia is the most prevalent neoplasia among children. Despite the tremendous achievements of state-of-the-art treatment strategies, drug resistance is still a major cause of chemotherapy failure leading to relapse in pediatric acute lymphoblastic leukemia....
Main Authors: | Huiqin Chen, Dihua Zhang, Guoping Zhang, Xiaofeng Li, Ying Liang, Mohan Vamsi Kasukurthi, Shengyu Li, Glen M. Borchert, Jingshan Huang |
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Format: | Article |
Language: | English |
Published: |
BMC
2018-07-01
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Series: | BMC Medical Informatics and Decision Making |
Subjects: | |
Online Access: | http://link.springer.com/article/10.1186/s12911-018-0637-3 |
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