Modelling of absorption, distribution and physicochemical properties of AT1 receptor antagonists / Modelovanie absorpcie, distribúcie a fyzikálnochemických vlastnosti antagonistov AT1 receptorov
The theoretical chemistry methods were used to elucidate absorption, distribution and physicochemical properties of AT1 receptor antagonists and dual angiotensin II and endothelin A receptor antagonist (PS-433540). Computed partition coefficients (ALOGPS method) studied for drugs varied between 2.98...
Main Authors: | Ježko Pavol, Žufková Viera, Remko Milan |
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Format: | Article |
Language: | English |
Published: |
Sciendo
2015-12-01
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Series: | Acta Facultatis Pharmaceuticae Universitatis Comenianae |
Subjects: | |
Online Access: | https://doi.org/10.1515/afpuc-2015-0028 |
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