Modelling of absorption, distribution and physicochemical properties of AT1 receptor antagonists / Modelovanie absorpcie, distribúcie a fyzikálnochemických vlastnosti antagonistov AT1 receptorov

Modelling of absorption, distribution and physicochemical properties of AT1 receptor antagonists / Modelovanie absorpcie, distribúcie a fyzikálnochemických vlastnosti antagonistov AT1 receptorov

The theoretical chemistry methods were used to elucidate absorption, distribution and physicochemical properties of AT1 receptor antagonists and dual angiotensin II and endothelin A receptor antagonist (PS-433540). Computed partition coefficients (ALOGPS method) studied for drugs varied between 2.98...

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Bibliographic Details
Main Authors: Ježko Pavol, Žufková Viera, Remko Milan
Format: Article
Language:English
Published: Sciendo 2015-12-01
Series:Acta Facultatis Pharmaceuticae Universitatis Comenianae
Subjects:
at1 receptor antagonists
physicochemical properties
absorption
distribution
Online Access:https://doi.org/10.1515/afpuc-2015-0028

Internet

https://doi.org/10.1515/afpuc-2015-0028

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