Transcriptional networks in epithelial-mesenchymal transition.

Epithelial-mesenchymal transition (EMT) changes polarized epithelial cells into migratory phenotypes associated with loss of cell-cell adhesion molecules and cytoskeletal rearrangements. This form of plasticity is seen in mesodermal development, fibroblast formation, and cancer metastasis.Here we id...

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Bibliographic Details
Main Authors: Christo Venkov, David Plieth, Terri Ni, Amitava Karmaker, Aihua Bian, Alfred L George, Eric G Neilson
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2011-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3184133?pdf=render