Granulocyte-macrophage stimulating factor (GM-CSF) increases circulating dendritic cells but does not abrogate suppression of adaptive cellular immunity in patients with metastatic colorectal cancer receiving chemotherapy

<p>Abstract</p> <p>Background</p> <p>Advanced cancer and chemotherapy are both associated with immune system suppression. We initiated a clinical trial in patients receiving chemotherapy for metastatic colorectal cancer to determine if administration of GM-CSF in this s...

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Bibliographic Details
Main Authors: Martinez Micaela, Ono Nadia, Planutiene Marina, Planutis Kestutis, Nelson Edward L, Holcombe Randall F
Format: Article
Language:English
Published: BMC 2012-01-01
Series:Cancer Cell International
Online Access:http://www.cancerci.com/content/12/1/2