Neurofibromatosis 2: rare constellation of findings with extensive cranial nerve involvement

Neurofibromatosis 2: rare constellation of findings with extensive cranial nerve involvement

In this report, we aim to present a sporadic case of a 17-year old female patient who presented to the Radiodiagnosis department in JSS Hospital, Mysuru, India with complaints of insidious onset of difficulty in walking, motor & sensory impairment, slurring of speech, difficulty in food inge...

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Main Authors: Rudresh Hiremath, MD, EDIR, Vishnu Dakshin, MBBS, MD, Sonal Agrawal, MBBS, MD
Format: Article
Language:English
Published: Elsevier 2021-01-01
Series:Radiology Case Reports
Online Access:http://www.sciencedirect.com/science/article/pii/S1930043320305689
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spelling doaj-2970a07802db4f83969a55dd05eee3532020-12-01T04:05:13ZengElsevierRadiology Case Reports1930-04332021-01-01161157165Neurofibromatosis 2: rare constellation of findings with extensive cranial nerve involvementRudresh Hiremath, MD, EDIR0Vishnu Dakshin, MBBS, MD1Sonal Agrawal, MBBS, MD2JSS Medical college, Mysuru, Karnataka 570004Corresponding author. (V. Dakshin); JSS Medical college, Mysuru, Karnataka 570004JSS Medical college, Mysuru, Karnataka 570004In this report, we aim to present a sporadic case of a 17-year old female patient who presented to the Radiodiagnosis department in JSS Hospital, Mysuru, India with complaints of insidious onset of difficulty in walking, motor & sensory impairment, slurring of speech, difficulty in food ingestion, and hearing impairment. Magnetic resonance imaging revealed bilateral vestibular & non vestibular Schwannomas with extensive cranial nerve involvement, multiple spinal & falcine meningiomas, and cervicodorsal intramedullary ependymoma amongst other findings. These core features give rise to the acronym MISME, which describes Multiple Inherited Schwannomas, Meningiomas and Ependymomas. This case is being reported to highlight the rare constellation of multiple cranial nerve Schwannomas, meningiomas, ependymomas and other peripheral nerve sheath tumors in a single patient and will add to the evidence of MISME in world literature.http://www.sciencedirect.com/science/article/pii/S1930043320305689
collection DOAJ
language English
format Article
sources DOAJ
author Rudresh Hiremath, MD, EDIR
Vishnu Dakshin, MBBS, MD
Sonal Agrawal, MBBS, MD
spellingShingle Rudresh Hiremath, MD, EDIR
Vishnu Dakshin, MBBS, MD
Sonal Agrawal, MBBS, MD
Neurofibromatosis 2: rare constellation of findings with extensive cranial nerve involvement
Radiology Case Reports
author_facet Rudresh Hiremath, MD, EDIR
Vishnu Dakshin, MBBS, MD
Sonal Agrawal, MBBS, MD
author_sort Rudresh Hiremath, MD, EDIR
title Neurofibromatosis 2: rare constellation of findings with extensive cranial nerve involvement
title_short Neurofibromatosis 2: rare constellation of findings with extensive cranial nerve involvement
title_full Neurofibromatosis 2: rare constellation of findings with extensive cranial nerve involvement
title_fullStr Neurofibromatosis 2: rare constellation of findings with extensive cranial nerve involvement
title_full_unstemmed Neurofibromatosis 2: rare constellation of findings with extensive cranial nerve involvement
title_sort neurofibromatosis 2: rare constellation of findings with extensive cranial nerve involvement
publisher Elsevier
series Radiology Case Reports
issn 1930-0433
publishDate 2021-01-01
description In this report, we aim to present a sporadic case of a 17-year old female patient who presented to the Radiodiagnosis department in JSS Hospital, Mysuru, India with complaints of insidious onset of difficulty in walking, motor & sensory impairment, slurring of speech, difficulty in food ingestion, and hearing impairment. Magnetic resonance imaging revealed bilateral vestibular & non vestibular Schwannomas with extensive cranial nerve involvement, multiple spinal & falcine meningiomas, and cervicodorsal intramedullary ependymoma amongst other findings. These core features give rise to the acronym MISME, which describes Multiple Inherited Schwannomas, Meningiomas and Ependymomas. This case is being reported to highlight the rare constellation of multiple cranial nerve Schwannomas, meningiomas, ependymomas and other peripheral nerve sheath tumors in a single patient and will add to the evidence of MISME in world literature.
url http://www.sciencedirect.com/science/article/pii/S1930043320305689
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AT vishnudakshinmbbsmd neurofibromatosis2rareconstellationoffindingswithextensivecranialnerveinvolvement
AT sonalagrawalmbbsmd neurofibromatosis2rareconstellationoffindingswithextensivecranialnerveinvolvement
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