Emergence of cytotoxic resistance in cancer cell populations*

Emergence of cytotoxic resistance in cancer cell populations*

We formulate an individual-based model and an integro-differential model of phenotypic evolution, under cytotoxic drugs, in a cancer cell population structured by the expression levels of survival-potential and proliferation-potential. We apply these models to a recently studied experimental system....

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Bibliographic Details
Main Authors:	Lorenzi Tommaso, Chisholm Rebecca H., Lorz Alexander, Larsen Annette K., de Almeida Luís Neves, Escargueil Alexandre, Clairambault Jean
Format:	Article
Language:	English
Published:	EDP Sciences 2015-01-01
Series:	ITM Web of Conferences
Online Access:	http://dx.doi.org/10.1051/itmconf/20150500009

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