Cullin 3 Recognition Is Not a Universal Property among KCTD Proteins.

Cullin 3 (Cul3) recognition by BTB domains is a key process in protein ubiquitination. Among Cul3 binders, a great attention is currently devoted to KCTD proteins, which are implicated in fundamental biological processes. On the basis of the high similarity of BTB domains of these proteins, it has b...

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Bibliographic Details
Main Authors: Giovanni Smaldone, Luciano Pirone, Nicole Balasco, Sonia Di Gaetano, Emilia Maria Pedone, Luigi Vitagliano
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2015-01-01
Series:PLoS ONE
Online Access:https://doi.org/10.1371/journal.pone.0126808