Insights into the Immunopathophysiology of Severe COVID-19 in Metabolic Disorders

Coronavirus disease 2019 (COVID-19) has affected millions of people across the world but disproportionately and severely affects persons with metabolic disorders such as obesity, diabetes mellitus, and hypertension. In this brief review, we discuss the pathways of immune dysregulation that may lead...

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Main Authors: Skand Shekhar, Caroline E. Copacino, Francisco J. Barrera, Janet E. Hall, Fady Hannah-Shmouni
Format: Article
Language:English
Published: Thieme Medical and Scientific Publishers Pvt. Ltd. 2020-04-01
Series:Annals of the National Academy of Medical Sciences (India)
Subjects:
Online Access:http://www.thieme-connect.de/DOI/DOI?10.1055/s-0040-1713346
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spelling doaj-295bfbda39514206a7e16ba9cb008e082021-04-02T09:30:34ZengThieme Medical and Scientific Publishers Pvt. Ltd.Annals of the National Academy of Medical Sciences (India)0379-038X2454-56352020-04-01560211211510.1055/s-0040-1713346Insights into the Immunopathophysiology of Severe COVID-19 in Metabolic DisordersSkand Shekhar0Caroline E. Copacino1Francisco J. Barrera2Janet E. Hall3Fady Hannah-Shmouni4Section on Endocrinology & Genetics, Eunice Kennedy Shriver National Institute of Child Health and Human Development, National Institutes of Health, Bethesda, Maryland, United StatesTufts University School of Medicine, Boston, Massachusetts, United StatesEndocrinology Division, Internal Medicine Department, University Hospital “Dr. Jose E. Gonzalez,” Universidad Autonoma de Nuevo Leon, Monterrey, MexicoClinical Research Branch, National Institute of Environmental Health Sciences, National Institutes of Health, Research Triangle Park, North Carolina, United StatesSection on Endocrinology & Genetics, Eunice Kennedy Shriver National Institute of Child Health and Human Development, National Institutes of Health, Bethesda, Maryland, United StatesCoronavirus disease 2019 (COVID-19) has affected millions of people across the world but disproportionately and severely affects persons with metabolic disorders such as obesity, diabetes mellitus, and hypertension. In this brief review, we discuss the pathways of immune dysregulation that may lead to severe COVID-19 in persons with metabolic conditions.http://www.thieme-connect.de/DOI/DOI?10.1055/s-0040-1713346covid-19diabetes mellitushypertensionobesity
collection DOAJ
language English
format Article
sources DOAJ
author Skand Shekhar
Caroline E. Copacino
Francisco J. Barrera
Janet E. Hall
Fady Hannah-Shmouni
spellingShingle Skand Shekhar
Caroline E. Copacino
Francisco J. Barrera
Janet E. Hall
Fady Hannah-Shmouni
Insights into the Immunopathophysiology of Severe COVID-19 in Metabolic Disorders
Annals of the National Academy of Medical Sciences (India)
covid-19
diabetes mellitus
hypertension
obesity
author_facet Skand Shekhar
Caroline E. Copacino
Francisco J. Barrera
Janet E. Hall
Fady Hannah-Shmouni
author_sort Skand Shekhar
title Insights into the Immunopathophysiology of Severe COVID-19 in Metabolic Disorders
title_short Insights into the Immunopathophysiology of Severe COVID-19 in Metabolic Disorders
title_full Insights into the Immunopathophysiology of Severe COVID-19 in Metabolic Disorders
title_fullStr Insights into the Immunopathophysiology of Severe COVID-19 in Metabolic Disorders
title_full_unstemmed Insights into the Immunopathophysiology of Severe COVID-19 in Metabolic Disorders
title_sort insights into the immunopathophysiology of severe covid-19 in metabolic disorders
publisher Thieme Medical and Scientific Publishers Pvt. Ltd.
series Annals of the National Academy of Medical Sciences (India)
issn 0379-038X
2454-5635
publishDate 2020-04-01
description Coronavirus disease 2019 (COVID-19) has affected millions of people across the world but disproportionately and severely affects persons with metabolic disorders such as obesity, diabetes mellitus, and hypertension. In this brief review, we discuss the pathways of immune dysregulation that may lead to severe COVID-19 in persons with metabolic conditions.
topic covid-19
diabetes mellitus
hypertension
obesity
url http://www.thieme-connect.de/DOI/DOI?10.1055/s-0040-1713346
work_keys_str_mv AT skandshekhar insightsintotheimmunopathophysiologyofseverecovid19inmetabolicdisorders
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AT franciscojbarrera insightsintotheimmunopathophysiologyofseverecovid19inmetabolicdisorders
AT janetehall insightsintotheimmunopathophysiologyofseverecovid19inmetabolicdisorders
AT fadyhannahshmouni insightsintotheimmunopathophysiologyofseverecovid19inmetabolicdisorders
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