Decellularized skeletal muscles display neurotrophic effects in three‐dimensional organotypic cultures

Decellularized skeletal muscles display neurotrophic effects in three‐dimensional organotypic cultures

Abstract Skeletal muscle decellularization allows the generation of natural scaffolds that retain the extracellular matrix (ECM) mechanical integrity, biological activity, and three‐dimensional (3D) architecture of the native tissue. Recent reports showed that in vivo implantation of decellularized...

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Bibliographic Details
Main Authors: Paolo Raffa, Valentina Scattolini, Mattia Francesco Maria Gerli, Silvia Perin, Meihua Cui, Paolo De Coppi, Nicola Elvassore, Paola Caccin, Camilla Luni, Anna Urciuolo
Format: Article
Language:English
Published: Wiley 2020-10-01
Series:Stem Cells Translational Medicine
Subjects:
3D culture
axons
decellularized muscle
ECM
innervation
neurons
Online Access:https://doi.org/10.1002/sctm.20-0090

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