Regional differences in islet distribution in the human pancreas--preferential beta-cell loss in the head region in patients with type 2 diabetes.

Regional differences in islet distribution in the human pancreas--preferential beta-cell loss in the head region in patients with type 2 diabetes.

While regional heterogeneity in islet distribution has been well studied in rodents, less is known about human pancreatic histology. To fill gaps in our understanding, regional differences in the adult human pancreas were quantitatively analyzed including the pathogenesis of type 2 diabetes (T2D). C...

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Bibliographic Details
Main Authors: Xiaojun Wang, Ryosuke Misawa, Mark C Zielinski, Peter Cowen, Junghyo Jo, Vipul Periwal, Camillo Ricordi, Aisha Khan, Joel Szust, Junhui Shen, J Michael Millis, Piotr Witkowski, Manami Hara
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2013-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3691162?pdf=render

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