Prevalence of ultrasonography proved polycystic ovaries in North Indian women with type 2 diabetes mellitus

• Main Authors: Laway Bashir A, Bashir Mir I, Masoodi Shariq R, Wani Arshad I, Gupta Vipin K, Zargar Abdul H, Ganie Mohammad A, Salahuddin Mohammad
• Format: Article
• Language: English
• Published: BMC 2005-08-01
• Series: Reproductive Biology and Endocrinology
• Online Access: http://www.rbej.com/content/3/1/35

<p>Abstract</p> <p>Background</p> <p>Polycystic ovaries (PCO) and their clinical expression (the polycystic ovary syndrome [PCOS]) as well as type 2 diabetes mellitus (T2DM) are common medical conditions linked through insulin resistance. We studied the prevalence of PCO and PCOS in women with diet and/or oral hypoglycemic treated T2DM and non-diabetic control women.</p> <p>Design</p> <p>Prospective study.</p> <p>Methods</p> <p>One hundred and five reproductive age group women with diet and /or oral hypoglycemic treated T2DM were the subjects of the study. Sixty age-matched non-diabetic women served as controls. Transabdominal ultrasonographic assessment of the ovaries was used to diagnose PCO. Clinical, biochemical and hormonal parameters were also noted.</p> <p>Results</p> <p>Ultrasonographic prevalence of PCO was higher in women with diabetes than in non-diabetic subjects (61.0% vs. 36.7%, P < 0.003) whereas that of PCOS was 37.1% in diabetic subjects and 25% in non-diabetic controls (P > 0.1). Diabetic women with PCO had diabetes of significantly longer duration than those without PCO (4.19±2.0 versus 2.9±1.6 yrs; p < 0.05). Among both diabetic and non-diabetic women, those with PCO had significantly higher plasma LH, LH/FSH ratio, total testosterone and androstenedione levels.</p> <p>Conclusion</p> <p>This study demonstrates a higher prevalence of PCO in women with T2DM as compared to non-diabetic subjects.</p>