Positional information generated by spatially distributed signaling cascades.

The temporal and stationary behavior of protein modification cascades has been extensively studied, yet little is known about the spatial aspects of signal propagation. We have previously shown that the spatial separation of opposing enzymes, such as a kinase and a phosphatase, creates signaling act...

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Bibliographic Details
Main Authors: Javier Muñoz-García, Zoltan Neufeld, Boris N Kholodenko
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2009-03-01
Series:PLoS Computational Biology
Online Access:http://europepmc.org/articles/PMC2654021?pdf=render